Matthew 24:21

21For 24:21 The most obvious sign during the tribulation, prior to the second coming of Jesus, is when the abomination that causes desolation (the Antichrist) sets his image in the temple.at that time there will be a great tribulation (pressure, distress, oppression), such as has not occurred since the beginning of the world until now, nor ever will [again]. [Dan 12:1; Joel 2:2]