2has in these last days spoken [with finality] to us in [the person of One who is by His character and nature] His Son [namely Jesus], whom He appointed heir and lawful owner of all things, through whom also He created the universe [that is, the universe as a space-time-matter continuum].
2But in these last days, he has spoken to us through his Son. He is the one whom God appointed to receive all things. God also made everything through him.
2But in these last days, he has spoken to us in his Son. In the beginning, God worked through his Son to make the whole universe. He decided that everything should belong to his Son.